Vaccine/Antibody updates

[jficke13]

I feel like Norway is 0. I mean Bernie's far left by USA standards but he's just another democratic socialist anywhere else.

That is kind of funny to think about. The CDU/CSU in Germany is a "conservative" party, and they'd be excoriated as commie swine here.

[tower912]

I will get the Pfizer booster when offered.

[4everwarriors]

I will get the Pfizer booster when offered.

Why? You've been vaccinated and have had covid. People are making decisions on a daily basis without understanding the science. It makes zero sense, hey?

[jesmu84]

I will get the Pfizer booster when offered.

Would make more sense to get a titer first.

If titers are even a thing with mRNA vaccines

[tower912]

Why? You've been vaccinated and have had covid. People are making decisions on a daily basis without understanding the science. It makes zero sense, hey?

Pfizer says their vaccine antibodies diminishes over time.   Delta is coming.   Stupid not to.    I've had it.   It sucks.  I don't want it again.

You need to keep up.

[The Sultan]

Pfizer says their vaccine antibodies diminishes over time.   Delta is coming.   Stupid not to.    I've had it.   It sucks.  I don't want it again.

You need to keep up.

Yep I will get a booster when it's suggested.

[4everwarriors]

Fahrenheit, you likely have immunity having contracted the disease.

[The Sultan]

Fahrenheit, you likely have immunity having contracted the disease.

For now...

[The Sultan]

Just announced. No booster needed.

https://twitter.com/saraecook/status/1413307740026507269?s=21

[4everwarriors]

Reality is we don't know the long term effects of the disease, nor do we know the long term effects of the vaccine.

[tower912]

Not yet.   I have always assumed that there would be an annual booster, similar to a flu shot.   I don't consider it that interesting or controversial.   But I never felt like was mask was a burden either.

[JWags85]

Not yet.   I have always assumed that there would be an annual booster, similar to a flu shot.   I don't consider it that interesting or controversial.   But I never felt like was mask was a burden either.

I firmly disagree on the last point, but otherwise I agree.  Many common vaccines need boosters or annual shots.  Not sure why people are stressing about it

[The Sultan]

Reality is we don't know the long term effects of the disease, nor do we know the long term effects of the vaccine.

There aren't long term effects of the vaccine. That's nonsense.

[cheebs09]

For a booster, is it the same exact shot? Or tweaked from the initial vaccine? I'm curious from a production standpoint if things will be pretty smooth, especially as demand has dropped. Or if a ramp up will be needed.

[Frenns Liquor Depot]

I think everyone is getting ahead of themselves.  Give it a week or two.  We can argue then.

[pbiflyer]

Just announced. No booster needed.

https://twitter.com/saraecook/status/1413307740026507269?s=21

Pfizer disagrees:
Pfizer sees waning immunity from its Covid-19 vaccine, says developing new booster.
https://www.cnn.com/2021/07/08/health/pfizer-waning-immunity-bn/index.html

"As seen in real world data released from the Israel Ministry of Health, vaccine efficacy in preventing both infection and symptomatic disease has declined six months post-vaccination, although efficacy in preventing serious illnesses remains high," the company said in a statement emailed to CNN.

[The Sultan]

Pfizer disagrees:
Pfizer sees waning immunity from its Covid-19 vaccine, says developing new booster.
https://www.cnn.com/2021/07/08/health/pfizer-waning-immunity-bn/index.html

"As seen in real world data released from the Israel Ministry of Health, vaccine efficacy in preventing both infection and symptomatic disease has declined six months post-vaccination, although efficacy in preventing serious illnesses remains high," the company said in a statement emailed to CNN.

I trust the CDC, FDA and NIH more than Pfizer.

[ZiggysFryBoy]

I trust the CDC, FDA and NIH more than Pfizer.

In other news, Moderna and J&J agree with Pfizer, hey?

[jesmu84]

I trust the CDC, FDA and NIH more than Pfizer.

At this point, I'm so confused on who we're supposed to trust when.

[forgetful]

I trust the CDC, FDA and NIH more than Pfizer.

The statement from them indicated that a booster is not needed now, but indicated they are actively testing boosters.

Translation for the lay-person. You will need a booster soon, but one isn't approved, or ready yet, so we will tell you one isn't needed (most have been vaccinated in the past 6-months). This statement will change as soon as boosters are ready.

The real world data in places like Israel clearly shows we will require boosters as soon as they are ready.

Immunity to the Delta variant down to 63%.

[JWags85]

Immunity to the Delta variant down to 63%.

Can you explain this?  63% of the vaccinated population is immune to the variant?

[The Sultan]

The statement from them indicated that a booster is not needed now, but indicated they are actively testing boosters.

Translation for the lay-person. You will need a booster soon, but one isn't approved, or ready yet, so we will tell you one isn't needed (most have been vaccinated in the past 6-months). This statement will change as soon as boosters are ready.

The real world data in places like Israel clearly shows we will require boosters as soon as they are ready.

Immunity to the Delta variant down to 63%.

Gotcha

[Hards Alumni]

At this point, I'm so confused on who we're supposed to trust when.

Pfizer disagrees:
Pfizer sees waning immunity from its Covid-19 vaccine, says developing new booster.
https://www.cnn.com/2021/07/08/health/pfizer-waning-immunity-bn/index.html

"As seen in real world data released from the Israel Ministry of Health, vaccine efficacy in preventing both infection and symptomatic disease has declined six months post-vaccination, although efficacy in preventing serious illnesses remains high," the company said in a statement emailed to CNN.

Follow the cash

[forgetful]

Can you explain this?  63% of the vaccinated population is immune to the variant?

The value is calculated as the relative difference in risk between two populations, divided by the risk in the unvaccinated group, or 1-risk ratio.

So if 10% of the unvaccinated population was testing positive, and only 0.5% of the vaccinated the efficacy would be:

(0.10-0.005)/0.10 or 95%. That was the original efficacy. Or equivalently, 1 - (0.5/10)=0.95 (95% fewer cases)

For delta in Israel, right now they are seeing an efficacy of 63%, so if we assume the same 10% rate in unvaccinated, it would imply the risk to the vaccinated is now 3.7%.

[Frenns Liquor Depot]

The value is calculated as the relative difference in risk between two populations, divided by the risk in the unvaccinated group, or 1-risk ratio.

So if 10% of the unvaccinated population was testing positive, and only 0.5% of the vaccinated the efficacy would be:

(0.10-0.005)/0.10 or 95%. That was the original efficacy. Or equivalently, 1 - (0.5/10)=0.95 (95% fewer cases)

For delta in Israel, right now they are seeing an efficacy of 63%, so if we assume the same 10% rate in unvaccinated, it would imply the risk to the vaccinated is now 3.7%.

Forgetful - is this calc against a positive test, symptomatic disease or severe disease.  My understanding are more people are getting infections, but most are not serious.  Still the case in Israel right?