Kolek planning to go pro
That's not how this works and you know it.Not with the delta variant. 70% would have been enough before delta spread. Now it's not.Science moves. Treatments change.
That’s right, forgot about delta….damn the luck!!!
Congrats on being the 2nd most disingenuous poster on the board
I believe I saw today we are now at Biden’s goal of 70% of Americans getting at least their first shot. So we hit his goal yet still seem to be on a path back to mask mandates and other restrictions. We did our part (generally speaking) and helped the administration hit their goal, albeit a couple weeks late. Now it’s their time to hold up their end of the bargain and let us return to normal without threat of increased restrictions etc.
When's it going to end, hey?
Disingenuous trolling. Again.
What’s disingenuous or trolling about that post? Biden said once we hit 70% we can go back to normal, we’re there and the vaccine is proving to be very effective against Delta?Do you not believe in the efficacy of the vaccine?
forgetful, gooo, care to weigh in on lambda?https://www.news-medical.net/news/20210730/Scientists-suspect-Lambda-SARS-CoV-2-variant-most-dangerous.aspx
We're all gonna die.
Are you concerned with unchecked spread of Delta through unvaccinated populations could lead to more variants that perhaps will be worse?Do you acknowledge that variables have changed since his statement?
And no I’m not concerned about the unchecked spread amongst the unvaccinated. They have had ample opportunity to get the poke.
Not if they are under 12. Also, while still very effective, I think vaccines are less effective against Delta.I’m vaccinated and not all that worried about Delta for myself. However, still nervous for my daughter. As others have said, unvaccinated is not just those who choose not to get the poke. The good news is I think the outcomes are still pretty good for kids with this.
No I don’t agree things have changed. There is a new variant that current vaccines are highly effective against in preventing serious illness and/or death. There were multiple variants then, there are multiple variants now. Until one proves resistant to any of the current vaccines what has really changed?
You missed the 2nd part of that question.
There have been a couple disheartening developments lately, both still not peer-reviewed (this is one of them). Lambda looks to combine the ease of spread of Delta with variants that evade the existing neutralizing antibodies. That's a bad combination. It also was prevalent in Chile, where vaccination rates are high.It highlights the risks of variants spreading widely amongst the vaccinated/unvaccinated. It puts a selective pressure (vaccination) on the virus that can lead to the emergence of escape variants. Let's see what additional research comes out on the degree to which Delta can escape existing vaccines. It is certainly a worrisome development.The other is data coming out of Rockefeller University that shows that although booster shots can increase antibody levels, they are unlikely to boost resistance to escape variants. Which means new versions of the vaccine will need to be developed. The good news is both Pfizer and Moderna are already looking at this...the question is which variant to design the booster vaccine off of.The good news from the Rockefeller study, those that were infected, and then later got a vaccine have antibodies that are broadly efficacious agains all current variants of concern.
Am i understanding escape variants correctly. They emerge from people getting the existing vaccines?
You are not. Variants emerge as due to natural selection. Variants that spread more readily eventually out compete (for hosts) other variants. This is most likely to occur as a natural process in unvaccinated individuals.What can occur in vaccinated/or previously infected individuals, is that over time selective pressures can develop, e.g. immunity to the original form of the virus, whether natural immunity or vaccine-based immunity. If a virus can get hold in these populations, possibly due to a weakened immune system, then any mutations that occur during normal replication that enhance infectivity will win. In my opinion, the presence of a selective pressure leads to a more likely possibility of an escape variant; albeit with a caveat...it is much less likely a virus will be replicating in a vaccinated host. We use these selective pressures in many laboratory experiments to evolve proteins, or organisms with desired traits. Although unlikely, a replicating virus in a "immune" host can lead to a true escape variant. That is why it is important to vaccinate EVERYONE. No hosts to spread, no risk of variants.There are some situations that can increase this low level likelihood though. Some of the original variants developed in people with compromised immune systems that retained low-level replicating virus for months. That kind of environment allows a lot of time for mutations to accumulate.
And we have teachers who don't want to teach, business owners who are either hurting or gone out completely, people who don't want to work, landlords who can't collect their due rent, unmeasurable psychological issues related to covid and its handling, etc., etc.When's it going to end, hey?