Oso planning to go pro
I think once we have a vaccine that works even as good as the flu vaccine, the whole masking and social distancing thing will go away pretty quickly. People will still get sick, but the numbers will fall off and serious spikes will be isolated and no longer all that newsworthy.
I respect our caution and your perspective, but let’s say you have a vaccine by Christmas. You’re talking mid 2021, aka another full year of expecting/asking people to mask up and socially distance. That’s a pretty big ask/hope if that’s how it’s gonna be beaten. Unless I am misunderstanding
I'm not an anti-vaxxer by any means. But if I think they've rushed something out, I'll wait 6 months before getting an injection. I'll still be cautious about interactions with people in the meantime. I'm not judging anybody that chooses to wait a bit if a vaccine is out late this year/early next. That's a ridiculously fast timeline to be "fully vetted"
Yeah, going "first" is uncomfortable.You know what I think I'll do? Ask my doctor. That guy knows medical stuff.
I'll go first. Someone has to.
If/when a vaccine is available. I encourage anyone getting it to get it in the morning, after at least 1-week of regular sleep cycles.
Might we see a world where we take the first available vaccine to slow this down significantly, while waiting for a better vaccine to confer better immunity in the long term?
Why?
I respect our caution and your perspective, but let’s say you have a vaccine by Christmas. You’re talking mid 2021, aka another full year of expecting/asking people to mask up and socially distance. That’s a pretty big ask/hope if that’s how it’s gonna be beaten. Unless I am misunderstanding You’ve been reasonable even when we disagree, so I’m not coming at you, but I’m just very curious on peoples perceptions of what they’d be “ok” with indefinitely if that’s the case.
If I am recalling correctly, the Oxford vaccine had gone through trials previously and been deemed safe long-term, so sign me up for that one.
Studies in recent years have shown that antibody response tends to be greater in the morning than later in the day, and that healthy sleep patterns increase the effectiveness of vaccines. A couple of examples:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874947/https://www.ucsf.edu/news/2012/08/12458/sleep-affects-potency-vaccines
AstraZeneca and Oxford announced their partnership on the vaccine on April 30. A 10,000-patient study testing the vaccine is being run in the United Kingdom, and a separate 5,000-patient test began in Brazil in June. Soriot, the AstraZeneca CEO, said that phase 3 results could become available in September, October, or November.
Rocky, where did you acquire the N95 masks? Online seems like a crap shoot.
I think this is AZD1222 (Oxford-AstraZeneca colab). They've gone through a phase 2 trial (~1000 people) with good results. The phase 3 is usually ~10,000 but they've got a bunch more signed up. That's good. Still, probably not available until next year though.https://www.statnews.com/2020/07/20/study-provides-first-glimpse-of-efficacy-of-oxford-astrazeneca-covid-19-vaccine/
I'm not expert, but I believe you're overestimating how quickly vaccines can be produced at scale and rolled out. Another year of social distancing is inevitable. The fastest multi-country new vaccine rollout in history took 2.5 years, and that was the new polio vaccine (so a well-known disease with a new variation of an existing vaccine).
Yeah, I guess I'm mostly expecting masking for another year regardless. Now that I've acquired enough masks that fit comfortably, and for enough situations (cloth/disposable for around town, N95 for planes and airports) they don't bother me much at all. And I'm *very* cautious, but I think I've been a little more "risky" than some here. I've been on 6 planes since May 1, another two coming up in the next couple weeks. Even stayed in a hotel for a couple nights. Masked up with N95 for the entire plane ride - and it was fine.
I’m not over estimating, much like Hards alluded to, I’m trying to figure out what a word with a vaccine, even early stages or initial roll outs would look like for people and their risk management.
Any thoughts from you guys in the know how a vaccine developed in another country would affect us?We are pretty much going it alone on a vaccine and I wonder where in the pecking order we would be if it is developed elsewhere. I’m guessing they would take care of themselves first, but would they share their findings with us? I’m guessing yes, but I don’t know how this works with proprietary products.