Hydroxychloroquinine updates (and other potential treatments)

[Frenns Liquor Depot]

Vindication:

https://twitter.com/jonathanchait/status/1293881975409958913?s=19

That’s hilarious.  Wonder if this will give our own HC license to post on his old (or most recent old) name.

 

[GooooMarquette]

Clinical Trials of Coronavirus Drugs Are Taking Longer Than Expected
 
https://www.nytimes.com/2020/08/14/health/covid-19-antibody-treatments.html?action=click&module=Top%20Stories&pgtype=Homepage

As the coronavirus pandemic continues to wreak havoc in the United States and treatments are needed more than ever, clinical trials for some of the most promising experimental drugs are taking longer than expected.

Researchers at a dozen clinical trial sites said that testing delays, staffing shortages, space constraints and reluctant patients were complicating their efforts to test monoclonal antibodies, man-made drugs that mimic the molecular soldiers made by the human immune system.

As a result, once-ambitious deadlines are slipping. The drug maker Regeneron, which previously said it could have emergency doses of its antibody cocktail ready by the end of summer, has shifted to talking about how “initial data” could be available by the end of September.

And Eli Lilly’s chief scientific officer said in June that its antibody treatment might be ready in September, but in an interview this week, he said he now hopes for something before the end of the year.

——————————

Unfortunate, but totally predictable given the uncertainties of clinical trials, combined with the ongoing (and appalling) shortage of tests.

[GooooMarquette]

Study Hints, Can't Prove, Survivor Plasma Fights COVID-19

https://www.nytimes.com/aponline/2020/08/14/health/ap-us-med-virus-outbreak-blood-of-the-recovered.html?searchResultPosition=9

Mayo Clinic researchers reported a strong hint that blood plasma from COVID-19 survivors helps other patients recover, but it’s not proof and some experts worry if, amid clamor for the treatment, they'll ever get a clear answer.

More than 64,000 patients in the U.S. have been given convalescent plasma, a century-old approach to fend off flu and measles before vaccines. It's a go-to tactic when new diseases come along, and history suggests it works against some, but not all, infections.

There’s no solid evidence yet that it fights the coronavirus and, if so, how best to use it. But preliminary data from 35,000 coronavirus patients treated with plasma offers what Mayo lead researcher Dr. Michael Joyner on Friday called “signals of efficacy.”

[Plaque Lives Matter!]

Oh good.

https://www.axios.com/trump-covid-oleandrin-9896f570-6cd8-4919-af3a-65ebad113d41.html?utm_source=twitter&utm_medium=social&utm_campaign=organic&utm_content=1100

[The Hippie Satan of Hyperbole]

Oh good.

https://www.axios.com/trump-covid-oleandrin-9896f570-6cd8-4919-af3a-65ebad113d41.html?utm_source=twitter&utm_medium=social&utm_campaign=organic&utm_content=1100

“ It's embraced by Housing and Urban Development Secretary Ben Carson and MyPillow founder and CEO Mike Lindell, a big Trump backer, who recently took a financial stake in the company that develops the product.”

Remember when four years ago statements like this would have been assumed to be fiction? 

[tower912]

Like the rest, I hope it works.   I doubt it.   Keep sciencing.   Beware snake oil salesmen.

[jesmu84]

Oh good.

https://www.axios.com/trump-covid-oleandrin-9896f570-6cd8-4919-af3a-65ebad113d41.html?utm_source=twitter&utm_medium=social&utm_campaign=organic&utm_content=1100

This is absolutely garbage:

The big picture: It's part of a pattern in which entrepreneurs, often without rigorous vetting, push unproven products to Trump — knowing their sales pitches might catch his eye. Trump will then urge FDA Commissioner Stephen Hahn to "look at" or speed up approval

.

[MU82]

Like the rest, I hope it works.   I doubt it.   Keep sciencing.   Beware snake oil salesmen.

What did the witch doctor think about it, I wonder?

[Billy Hoyle]

Like the rest, I hope it works.   I doubt it.   Keep sciencing.   Beware snake oil salesmen.

Anderson Cooper absolutely evicerated Dr. MyPillow Guy.

https://thehill.com/homenews/media/512546-cnns-cooper-to-mypillow-ceo-you-really-are-like-a-snake-oil-salesman

[TSmith34, Inc.]

Anderson Cooper absolutely evicerated Dr. MyPillow Guy.

https://thehill.com/homenews/media/512546-cnns-cooper-to-mypillow-ceo-you-really-are-like-a-snake-oil-salesman

Raving lunatic and con artist. Birds of a feather...

[pacearrow02]

https://losangeles.cbslocal.com/2020/08/18/covid-19-survivor-coronavirus-experimental-drug-leronlimab/amp/?__twitter_impression=true

[MU82]

https://losangeles.cbslocal.com/2020/08/18/covid-19-survivor-coronavirus-experimental-drug-leronlimab/amp/?__twitter_impression=true

Yeah, but what do witch doctors, Lou Dobbs and Dr. MyPillow think of it?

Seriously ... This is encouraging. I am glad it helped the woman in the video, and apparently other patients, too. If it saved even one life, it's a great thing. Like the doctor who was interviewed, I am optimistic about it and await results of scientific trials.

[Boone]

My Pillow clown probably did more for society when he was a coke head

[MU82]

This stinks, but I'm still hopeful longer-term.

https://www.nytimes.com/2020/08/19/us/politics/blood-plasma-covid-19.html?campaign_id=60&emc=edit_na_20200819&instance_id=0&nl=breaking-news&ref=headline&regi_id=108420427&segment_id=36506&user_id=d36dcf821462fdd16ec3636710a855fa

WASHINGTON — Last week, just as the Food and Drug Administration was preparing to issue an emergency authorization for blood plasma as a Covid-19 treatment, a group of top federal health officials including Dr. Francis S. Collins and Dr. Anthony S. Fauci intervened, arguing that emerging data on the treatment was too weak, according to two senior administration officials.

The authorization is on hold for now as more data is reviewed, according to H. Clifford Lane, the clinical director at the National Institute of Allergy and Infectious Diseases. An emergency approval could still be issued in the near future, he said.

Donated by people who have survived the disease, antibody-rich plasma is considered safe. President Trump has hailed it as a “beautiful ingredient” in the veins of people who have survived Covid-19.

But clinical trials have not proved whether plasma can help people fighting the coronavirus.

[Hards Alumni]

My Pillow clown probably did more for society when he was a coke head

Frankly, I'm still waiting for all the drive thru testing at CVS, Walgreens, Walmart and Target I was promised.  Plus the contact tracing by Google.

Wait, hold on... it was just a commercial for those companies, you say?  WHY HOW COULD THAT BE?

[The Hippie Satan of Hyperbole]

Expected

https://twitter.com/twittermoments/status/1272578311097548802?s=21

Inevitable

https://twitter.com/realdonaldtrump/status/1297148038385991680?s=21

[rocket surgeon]

Frankly, I'm still waiting for all the drive thru testing at CVS, Walgreens, Walmart and Target I was promised.  Plus the contact tracing by Google.

Wait, hold on... it was just a commercial for those companies, you say?  WHY HOW COULD THAT BE?

  here ya go frank-a very simple search could find the answer to many of your questions -the cvs near me uses one of their two drive thru lanes for covid testing only.  you've had to have seen this driving your seniors to their bingo et.al.

https://www.cvs.com/minuteclinic/covid-19-testing

[MU82]

It gets effen exhausting ...

https://www.miamiherald.com/news/article245162585.html?ac_cid=DM265468&ac_bid=1867225246

With Trump's political future hinging on his response to the COVID-19 pandemic and his promise to bring forth a vaccine by Election Day on Nov. 3, the U.S. Food and Drug Administration is now facing political pressure and rhetoric from the White House.

On Saturday, Trump suggested that employees at the FDA are attempting to sabotage his reelection by slowing down coronavirus research.

In a tweet, Trump said members of "the deep state" at the FDA are making it hard for drug companies to "get people in order to test the vaccines and therapeutics" and "obviously" want to delay progress until after Nov. 3, Election Day. He tagged FDA Commissioner Stephen Hahn, appointed by Trump in 2019, in the tweet.

There's no evidence that the scientists and staff of the FDA are delaying treatments or vaccines that would likely prevent tens of thousands of deaths in the U.S. and across the world in service of a secret anti-Trump agenda.

[Uncle Rico]

It gets effen exhausting ...

https://www.miamiherald.com/news/article245162585.html?ac_cid=DM265468&ac_bid=1867225246

With Trump's political future hinging on his response to the COVID-19 pandemic and his promise to bring forth a vaccine by Election Day on Nov. 3, the U.S. Food and Drug Administration is now facing political pressure and rhetoric from the White House.

On Saturday, Trump suggested that employees at the FDA are attempting to sabotage his reelection by slowing down coronavirus research.

In a tweet, Trump said members of "the deep state" at the FDA are making it hard for drug companies to "get people in order to test the vaccines and therapeutics" and "obviously" want to delay progress until after Nov. 3, Election Day. He tagged FDA Commissioner Stephen Hahn, appointed by Trump in 2019, in the tweet.

There's no evidence that the scientists and staff of the FDA are delaying treatments or vaccines that would likely prevent tens of thousands of deaths in the U.S. and across the world in service of a secret anti-Trump agenda.

President Pandemic could come out and say eat lead paint chips to ward off Covid and the cult would be eating lead paint chips by the wheelbarrow full.

[tower912]

I thought that sleeping on 'My Pillow' cured COVID.

[wadesworld]

Dumb and dangerous.

[rocket surgeon]

President Pandemic could come out and say eat lead paint chips to ward off Covid and the cult would be eating lead paint chips by the wheelbarrow full.

  "The Obama administration backed off the promise of 100 million doses by October but pegged the number at 40 million."

"By mid-October, however, when the demand for the vaccine was at its highest, supply fell dramatically short, with as few as 11 million doses on hand,"

“It is purely a fortuity that this isn’t one of the great mass casualty events in American history,” Ron Klain, who was Biden’s chief of staff at the time, said of H1N1 in 2019. “It had nothing to do with us doing anything right. It just had to do with luck."

if this were during trump's term, they would have tried to impeach him...again

[MU82]

if this were during trump's term, they would have tried to impeach him...again

Yep. As your emperor said: "Leadership -- whatever happens, you're responsible."

Unless he's the supposed leader. Then it's Obama's fault, and Biden's fault, and China's fault, and the libs' fault, and Fauci's fault, and the governors' fault, and the media's fault, and Europe's fault, and ...

"I don't take responsibility at all."

Looking forward to his next lecture on leadership!

[The Hippie Satan of Hyperbole]

  "The Obama administration backed off the promise of 100 million doses by October but pegged the number at 40 million."

"By mid-October, however, when the demand for the vaccine was at its highest, supply fell dramatically short, with as few as 11 million doses on hand,"

“It is purely a fortuity that this isn’t one of the great mass casualty events in American history,” Ron Klain, who was Biden’s chief of staff at the time, said of H1N1 in 2019. “It had nothing to do with us doing anything right. It just had to do with luck."

if this were during trump's term, they would have tried to impeach him...again

For what?  People not dying? 

I'm not exactly sure what you are getting at here.  Obama may have been wrong and just got lucky?  How does that exonerate a president who clearly was wrong and didn't get lucky?

Look, we all know what you are doing here.  You are shifting goalposts to justify your 2016 and 2020 votes.  And that's your right to do.  Just don't expect anyone to take you seriously about your evaluation of presidential performance in the future.

[Uncle Rico]

  "The Obama administration backed off the promise of 100 million doses by October but pegged the number at 40 million."

"By mid-October, however, when the demand for the vaccine was at its highest, supply fell dramatically short, with as few as 11 million doses on hand,"

“It is purely a fortuity that this isn’t one of the great mass casualty events in American history,” Ron Klain, who was Biden’s chief of staff at the time, said of H1N1 in 2019. “It had nothing to do with us doing anything right. It just had to do with luck."

if this were during trump's term, they would have tried to impeach him...again

That has nothing to do with President Pandemic’s handling of this or his peddling a remedy that has proven not to be the cure or effective.