Good Day for Horses and Livestock

[Uncle Rico]

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2789362?guestAccessKey=58760460-df0f-4790-9257-8f3682dca39b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=021822

Tough day for Buffons

[MUDPT]

Just came here to post this.

[Pakuni]

But Joe Rogan ...

[jesmu84]

But Joe Rogan ...

But rocket...

[Jockey]

From the study:

"In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness did not reduce the risk of developing severe disease compared with standard of care alone."


Duh..., you need to use it for more than 5 days

[pacearrow02]

From the study:

"In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness did not reduce the risk of developing severe disease compared with standard of care alone."


Duh..., you need to use it for more than 5 days

Also from the study

Results  Among 490 patients included in the primary analysis (mean [SD] age, 62.5 [8.7] years; 267 women [54.5%]), 52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease (relative risk [RR], 1.25; 95% CI, 0.87-1.80; P = .25). For all prespecified secondary outcomes, there were no significant differences between groups. Mechanical ventilation occurred in 4 (1.7%) vs 10 (4.0%) (RR, 0.41; 95% CI, 0.13-1.30; P = .17), intensive care unit admission in 6 (2.4%) vs 8 (3.2%) (RR, 0.78; 95% CI, 0.27-2.20; P = .79), and 28-day in-hospital death in 3 (1.2%) vs 10 (4.0%) (RR, 0.31; 95% CI, 0.09-1.11; P = .09). The most common adverse event reported was diarrhea (14 [5.8%] in the ivermectin group and 4 [1.6%] in the control group).


So 60% less mechanical ventilation in ivermectin group, 70% reduction in death, and 33% reduction in ICU admission. 

Or am I interpreting that wrong?

[MUDPT]

Also from the study

Results  Among 490 patients included in the primary analysis (mean [SD] age, 62.5 [8.7] years; 267 women [54.5%]), 52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease (relative risk [RR], 1.25; 95% CI, 0.87-1.80; P = .25). For all prespecified secondary outcomes, there were no significant differences between groups. Mechanical ventilation occurred in 4 (1.7%) vs 10 (4.0%) (RR, 0.41; 95% CI, 0.13-1.30; P = .17), intensive care unit admission in 6 (2.4%) vs 8 (3.2%) (RR, 0.78; 95% CI, 0.27-2.20; P = .79), and 28-day in-hospital death in 3 (1.2%) vs 10 (4.0%) (RR, 0.31; 95% CI, 0.09-1.11; P = .09). The most common adverse event reported was diarrhea (14 [5.8%] in the ivermectin group and 4 [1.6%] in the control group).


So 60% less mechanical ventilation in ivermectin group, 70% reduction in death, and 33% reduction in ICU admission. 

Or am I interpreting that wrong?

[TSmith34, Inc.]

But rocket...

Won't deter him in the least. He lives in a post-fact world.

[Uncle Rico]

Also from the study

Results  Among 490 patients included in the primary analysis (mean [SD] age, 62.5 [8.7] years; 267 women [54.5%]), 52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease (relative risk [RR], 1.25; 95% CI, 0.87-1.80; P = .25). For all prespecified secondary outcomes, there were no significant differences between groups. Mechanical ventilation occurred in 4 (1.7%) vs 10 (4.0%) (RR, 0.41; 95% CI, 0.13-1.30; P = .17), intensive care unit admission in 6 (2.4%) vs 8 (3.2%) (RR, 0.78; 95% CI, 0.27-2.20; P = .79), and 28-day in-hospital death in 3 (1.2%) vs 10 (4.0%) (RR, 0.31; 95% CI, 0.09-1.11; P = .09). The most common adverse event reported was diarrhea (14 [5.8%] in the ivermectin group and 4 [1.6%] in the control group).


So 60% less mechanical ventilation in ivermectin group, 70% reduction in death, and 33% reduction in ICU admission. 

Or am I interpreting that wrong?

You're wrong again.  Stick to Connect 4 with the elderly

[pacearrow02]

Sure, but the data below is also right there to read for yourself.  What is the definition of significant?  Was the data size too small or does it have to be a certain % or CI to be considered significant?

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

[tower912]

This must be some of the big news we were promised.

Snake.


Oil.

[rocky_warrior]

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

Well, by your logic, it appears by taking ivermectin makes you 20% more likely to progress to severe disease!  If you like that sales pitch, take all your want!

52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease

[tower912]

Well, by your logic, it appears by taking ivermectin makes you 20% more likely to progress to severe disease!  If you like that sales pitch, take all your want!

Please.

[TSmith34, Inc.]

Sure, but the data below is also right there to read for yourself.  What is the definition of significant?  Was the data size too small or does it have to be a certain % or CI to be considered significant?

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

[MU82]

Great. The Deep State has infiltrated Malaysian studies of the greatest Covid cure known to man (and horses)!

What they're not telling us is that Dominion rigged this study.

[pacearrow02]

All very serious answers.  You guys are doing great!

[ATL MU Warrior]

When I was a kid, I had a horse. His name was El Bandito. He was smarter than Pace and RoQQet combined.

[Pakuni]

All very serious answers.  You guys are doing great!

Troll big angry people no take troll seriously.

[pacearrow02]

Troll big angry people no take troll seriously.

Remember when you said I was wrong in saying the FDA delayed their decision regarding the Pfizer vaccine for young kids because it wasnt working?  Shocking, you were spreading misinformation.....again.

https://www.google.com/amp/s/www.wsj.com/amp/articles/lower-omicron-efficacy-delayed-fda-review-on-pfizer-shot-in-kids-under-5-11645192800

[Pakuni]

Remember when you said I was wrong in saying the FDA delayed their decision regarding the Pfizer vaccine for young kids because it wasnt working?  Shocking, you were spreading misinformation.....again.

https://www.google.com/amp/s/www.wsj.com/amp/articles/lower-omicron-efficacy-delayed-fda-review-on-pfizer-shot-in-kids-under-5-11645192800

You were wrong and remain wrong.
Maybe for once in your life you should read beyond the headline.

[MUDPT]

Sure, but the data below is also right there to read for yourself.  What is the definition of significant?  Was the data size too small or does it have to be a certain % or CI to be considered significant?

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

Easy answer is that it's not 10 vs. 4, it's 14 in 490.  There isn't enough clinical difference in the groups to say it's better or worse.

[rocky_warrior]

Easy answer is that it's not 10 vs. 4, it's 14 in 490.  There isn't enough clinical difference in the groups to say it's better or worse.

490 too big for pace. 14 ok.

[pacearrow02]

Easy answer is that it's not 10 vs. 4, it's 14 in 490.  There isn't enough clinical difference in the groups to say it's better or worse.

Ok that makes sense, thanks for the adult response.  Do you know what the difference needs to be in these types of studies to be found significant?  Again sincere questions as I have no idea.

[Hards Alumni]

You were wrong and remain wrong.
Maybe for once in your life you should read beyond the headline.

He is the poster child for cognitive bias.

[Boozemon Barro]

https://twitter.com/CaldronPool/status/1495738643180568577?t=jJbftALdkIirVnhE4scqJg&s=19

[TSmith34, Inc.]

Are you a dentist by any chance?

https://www.health.gov.au/health-alerts/covid-19/treatments

Not recommended for COVID-19
The TGA has not approved, and the National COVID-19 Clinical Evidence Taskforce guidelines do not recommend, the following treatments for COVID-19.

Ivermectin, doxycycline, zinc
There is not enough evidence to support the safe and effective use of these drugs (separately, or in combination) to prevent or treat COVID-19.

The Clinical Evidence Taskforce does not recommend the use of ivermectin, doxycycline or zinc outside of properly conducted clinical trials with appropriate ethical approval.

Hydroxychloroquine
The Clinical Evidence Taskforce strongly recommends that people do not use hydroxychloroquine to treat COVID-19.

Hydroxychloroquine has well known risks including:

toxic effects on the heart (potentially leading to heart attacks)

irreversible eye damage

lowering blood sugar levels (potentially leading to coma).

[thomaskyle]

This is not a double blind study.
This is only 490 people.
This is only people over 50.
This is a useless study.  Completely and totally.

[TSmith34, Inc.]

Where is your dental practice located?

[Skatastrophy]

This is not a double blind study.
This is only 490 people.
This is only people over 50.
This is a useless study.  Completely and totally.

I mean, if you can power a study better than those scientists maybe you should inform the scientific world how to do it?

[pacearrow02]

https://www.cureus.com/articles/82162-ivermectin-prophylaxis-used-for-covid-19-a-citywide-prospective-observational-study-of-223128-subjects-using-propensity-score-matching

Not to shabby for horse dewormer

[TSmith34, Inc.]

[ZiggysFryBoy]

WTF is with the seals?  It's fuggin weird, even for you.

[Skatastrophy]

WTF is with the seals?  It's fuggin weird, even for you.

They're sea lions, you rube.

[Lighthouse 84]

WTF is with the seals?  It's fuggin weird, even for you.

C'mon man!  Can't you recognize the true comedian that TSmith is??

[TSmith34, Inc.]

Those pictures are quite the opposite of attempting to be funny you dope.

[rocky_warrior]

Those pictures are quite the opposite of attempting to be funny you dope buffon.

fify

[Pakuni]

Largest trial to date of Ivermectin as a treatment for COVID finds ... it's pretty much useless.

But a trial involving 1,400 infected people at risk of severe disease found it did not do better than a placebo, The Wall Street Journal reports. It did not shorten hospitals stays, get the virus out of the body faster, or keep more people alive. "There was no indication that ivermectin is clinically useful," said Professor Edward Mills, one of the study's lead researchers.

https://www.wsj.com/articles/ivermectin-didnt-reduce-covid-19-hospitalizations-in-largest-trial-to-date-11647601200?mod=hp_lead_pos6

[pacearrow02]

Largest trial to date of Ivermectin as a treatment for COVID finds ... it's pretty much useless.

But a trial involving 1,400 infected people at risk of severe disease found it did not do better than a placebo, The Wall Street Journal reports. It did not shorten hospitals stays, get the virus out of the body faster, or keep more people alive. "There was no indication that ivermectin is clinically useful," said Professor Edward Mills, one of the study's lead researchers.

https://www.wsj.com/articles/ivermectin-didnt-reduce-covid-19-hospitalizations-in-largest-trial-to-date-11647601200?mod=hp_lead_pos6

Bummer!!  Do you have a link to the study, couldn't find it anywhere.  Strange how some studies have showed good outcomes and some haven't, is it a dosing thing you think they need to figure out?

Good news is it's not doing any additional harm it appears in all the studies.

[MU82]

Leftist Wall Street Journal just pushing the leftist "fear and control" line rather than the accepted medical wisdom behind horse de-wormer.

[Pakuni]

Bummer!!  Do you have a link to the study, couldn't find it anywhere.  Strange how some studies have showed good outcomes and some haven't, is it a dosing thing you think they need to figure out?

Good news is it's not doing any additional harm it appears in all the studies.

"Dr. Mills on Friday plans to present the findings, which have been accepted for publication in a major peer-reviewed medical journal."

Could you link some of the peer-reviewed trials showing the good outcomes from ivectermin?

[jesmu84]

"Dr. Mills on Friday plans to present the findings, which have been accepted for publication in a major peer-reviewed medical journal."

Could you link some of the peer-reviewed trials showing the good outcomes from ivectermin?

He has no interest in genuine discussion.

This is the game celebrating the dead

[TSmith34, Inc.]

Bummer!!  Do you have a link to the study, couldn't find it anywhere.  Strange how some studies have showed good outcomes and some haven't, is it a dosing thing you think they need to figure out?

Good news is it's not doing any additional harm it appears in all the studies.

[pacearrow02]

"Dr. Mills on Friday plans to present the findings, which have been accepted for publication in a major peer-reviewed medical journal."

Could you link some of the peer-reviewed trials showing the good outcomes from ivectermin?

https://www.sciencedirect.com/science/article/pii/S1201971221009887

[Skatastrophy]

https://www.sciencedirect.com/science/article/pii/S1201971221009887

Plastic surgeons doing a meta-analysis, lol

[Pakuni]

https://www.sciencedirect.com/science/article/pii/S1201971221009887

That's not a trial.
Didn't see anything about peer-reviewed.

[Hards Alumni]

That's not a trial.
Didn't see anything about peer-reviewed.

Spoiler alert:  He doesn't understand this stuff, or he is a sea lion.

[MU82]

Ivermectin Does Not Reduce Risk of Covid Hospitalization, Large Study Finds

"At some point it will become a waste of resources to continue studying an unpromising approach."

https://www.nytimes.com/2022/03/30/health/covid-ivermectin-hospitalization.html?campaign_id=60&emc=edit_na_20220330&instance_id=0&nl=breaking-news&ref=headline&regi_id=108420427&segment_id=87050&user_id=d36dcf821462fdd16ec3636710a855fa

The anti-parasitic drug ivermectin, which has surged in popularity as an alternative treatment for Covid-19 despite a lack of strong research to back it up, showed no sign of alleviating the disease, according to results of a large clinical trial published on Wednesday.

The study, which compared more than 1,300 people infected with the coronavirus in Brazil who received either ivermectin or a placebo, effectively ruled out the drug as a treatment for Covid, the study's authors said.

"There's really no sign of any benefit," said Dr. David Boulware, an infectious-disease expert at the University of Minnesota.

The researchers shared a summary of these results in August during an online presentation hosted by the National Institutes of Health, but the full data set had not been published until now in The New England Journal of Medicine.

"Now that people can dive into the details and the data, hopefully that will steer the majority of doctors away from ivermectin towards other therapies," Dr. Boulware said.

[pbiflyer]

Who could have predicted?

[The Sultan]

When it all comes together....

https://twitter.com/MollyBeck/status/1509514508531871745

Molly Beck
@MollyBeck
A Chippewa Falls attorney who is a key player in a movement to take the impossible step of decertifying the 2020 election is running for AG to use the office to launch homicide investigations of doctors who did not give ivermectin to dying covid patients.

[Uncle Rico]

When it all comes together....

https://twitter.com/MollyBeck/status/1509514508531871745

Molly Beck
@MollyBeck
A Chippewa Falls attorney who is a key player in a movement to take the impossible step of decertifying the 2020 election is running for AG to use the office to launch homicide investigations of doctors who did not give ivermectin to dying covid patients.

She's probably a Packers owner, too

[jesmu84]

Rocket is gonna be devastated by the horse dewormer update

[Uncle Rico]

Rocket is gonna be devastated by the horse dewormer update

Just wait until the studies come out

[TSmith34, Inc.]

When it all comes together....

https://twitter.com/MollyBeck/status/1509514508531871745

Molly Beck
@MollyBeck
A Chippewa Falls attorney who is a key player in a movement to take the impossible step of decertifying the 2020 election is running for AG to use the office to launch homicide investigations of doctors who did not give ivermectin to dying covid patients.

Before I decide whether or not to vote for her, I'd like to hear her views on all the trans people in the migrant caravans that are marching here armed with CRT to conduct the War on Christmas.

[Warriors4ever]

Also need to know whether she will investigate all the schools putting litter boxes in bathrooms for students who identify as cats.

[SERocks]

Also need to know whether she will investigate all the schools putting litter boxes in bathrooms for students who identify as cats.

Oh yeah.  I read about that.

[MU82]

According to HHS data:

Nearly 832K courses of Pfizer's (PFE) COVID-19 antiviral Paxlovid have been administered since Dec. 17, a figure more than three times higher than the second-most used therapeutic.

~269K doses of AstraZeneca's Evushield has been given, and ~251K doses of Merck's (MRK) Lagevrio (molnupiravir) have been administered.

~100K doses of Eli Lilly's (LLY) bebtelovimab have been given.

Idiot doctors keep forgetting to prescribe horse de-wormer. They must still be waiting for the evidence to emerge that we've been promised repeatedly here on Scoop.

[pbiflyer]

A doctor claimed he had a 'miracle cure' for covid. He's going to prison.
https://www.washingtonpost.com/nation/2022/05/31/covid-cure-doctor-jennings-staley/

In March and April of 2020, as the coronavirus spread and people isolated in their homes, a doctor in San Diego boasted that he had his hands on a "miracle cure," according to prosecutors — hydroxychloroquine.

In mass-marketing emails from his business, Skinny Beach Med Spa, Jennings Ryan Staley said the drug was included in his coronavirus "treatment kits," despite the medication becoming increasingly scarce. But Staley had a way of getting it, he later told an undercover federal agent. He planned to smuggle in a barrel of hydroxychloroquine powder with the help of a Chinese supplier, prosecutors said.
Staley was sentenced last week to 30 days in prison and a year of home confinement for the scheme.

[tower912]

Good.   Liar and grifter.

[rocky_warrior]

Some good news for the off-label covid cure crowd (not a cure, more study needed). But still bad news for the horse dewormer crowd.

https://scitechdaily.com/common-medication-found-effective-at-reducing-odds-of-serious-outcomes-for-covid-19-patients/

[Skatastrophy]

Some good news for the off-label covid cure crowd (not a cure, more study needed). But still bad news for the horse dewormer crowd.

https://scitechdaily.com/common-medication-found-effective-at-reducing-odds-of-serious-outcomes-for-covid-19-patients/

Horse dewormer still tastes good. Can't say the same for the vaccine

[pbiflyer]

Another prominent doctor advocated horse paste.
Hydroxychloroquine as a COVID-19 treatment

Oz was among the medical experts to tout the benefits of hydroxychloroquine, the malaria drug pushed by former President Donald Trump as a treatment for COVID-19, despite insufficient evidence.

https://www.politico.com/minutes/congress/08-24-2022/ozs-early-covid-push/

[TSmith34, Inc.]

This must be the study roqqet has been waiting for! Proof that ivermectin works!

Errrr, what? Oh, it doesn't work? Nevermind then, I'm sure the deep state is continuing to suppress all the real data.


Ivermectin — a drug once touted as a Covid treatment by conservatives — doesn't improve recovery much, clinical trial finds
https://www.msn.com/en-us/health/medical/ivermectin-a-drug-once-touted-as-a-covid-treatment-by-conservatives-doesn-t-improve-recovery-much-clinical-trial-finds/ar-AA13kDJp

* A team of scientists affiliated with Duke University found that ivermectin does not meaningful improve the recovery of people with mild to moderate Covid.

* "These findings do not support the use of ivermectin in patients with mild to moderate COVID-19," they concluded.

* A previous study found that ivermectin does not lower the risk of hospitalization from Covid.

Early on in the pandemic when there were few treatment options, ivermectin gained national notoriety when a couple groups of conservative doctors, including Front Line COVID-19 Critical Care Alliance and America's Frontline Doctors began touting the drug on social media and elsewhere as a treatment for Covid. But there was little data backing up those claims and a study by Dr. Pierre Kory, a critical care physician in Wisconsin and president of the critical care alliance, claiming it was an effective treatment was later retracted for having flawed data."

*The FDA has warned people against taking the tablets for anything other than their approved use.

[Jay Bee]

Masks, once said unnecessary by fauci....

[tower912]

Ability to learn and adapt based on new information...

Facts. 

Focusing on Fauci from 2.5 years ago is the equivalent of focusing on team free throw percentage and ignoring the efg%.

Ivermectin is the Washington Generals Of COVID treatment.

You may as well be arguing for the efficiency of the 20 foot jumper.

Wait.  That isn't fair to the 20 foot jumper.  They occasionally go in.

[Skatastrophy]

Ability to learn and adapt based on new information...

Facts. 

Focusing on Fauci from 2.5 years ago is the equivalent of focusing on team free throw percentage and ignoring the efg%.

Ivermectin is the Washington Generals Of COVID treatment.

You may as well be arguing for the efficiency of the 20 foot jumper.

Wait.  That isn't fair to the 20 foot jumper.  They occasionally go in.

Doctors once said washing your hands is silly. That's why I don't wash my hands. That's also why I don't listen to those flip-floppin doctors.

[Uncle Rico]

Doctors once said washing your hands is silly. That's why I don't wash my hands. That's also why I don't listen to those flip-floppin doctors.

I use leeches on my athlete's foot

[tower912]

I chew twigs and bark to clean my teeth.

[🏀]

[Pakuni]

[rocky_warrior]

Why are children under 6 excluded.  It could be a treatment for RSV too!

[🏀]

Why are children under 6 excluded.  It could be a treatment for RSV too!

Children under 6 can't have RSV yet. They're lungs just haven't had time to build a good immune system yet.

[pbiflyer]

I only smoke Winston cigarettes because they are the ones recommended by doctors!

[JWags85]

To be fair, they were the crude old fashioned version of an inhaler.  They weren't true tobacco/nicotine cigarettes.  More like medicated/herbal vapor treatments.  Though one of the key active ingredients was usually stramonium, which while often effective as a respiratory treatment, is kind of gnarly.  So problematic in a different sort of way.

Come to think of it, I could see Aaron Rodgers being pretty into some stramonium herbal cigs these days

[MU82]

Come to think of it, I could see Aaron Rodgers being pretty into some stramonium herbal cigs these days

And then claiming he's "immunized."

[TSmith34, Inc.]

His stache has me sold

[lawdog77]

His stache has me sold

He's got nothin on these guys
https://www.boredpanda.com/2017-world-beard-moustache-championship-greg-anderson/?utm_source=google&utm_medium=organic&utm_campaign=organic