Kolek planning to go pro
Apologies for being lazy and not looking it up myself. How is the 90% calculated? Is it that 90% less trial participants have contracted covid than a similar representative control group? Or 90% more show antibodies? Just curious.
The article I read said they wanted 2 more months of data. I think it was partially inaccurate (likely journalist mis-stating aspects of an interview), in that they need a minimum of 2-months of safety data. Looks to be on track for initial use by late December.
Here is a link from the NIH, but I'm not smart enough to read it.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7361120/
If I were to bet, from here forward shut-downs are going to be dictated at the local and state level and will be based on hospital stress. Also, we know more about what needs to close, so more targeted versus blanket.Like this: https://kutv.com/news/coronavirus/gov-herbert-declares-new-state-of-emergency-to-address-hospital-overcrowding-case-surgeAlso notice who was referenced as providing advice from the the Feds.All this news makes the Scott Atlas experiment look really silly...
I have a feeling more and more state and local officials will be listening directly to Fauci, Birx and Redfield, and simply ignoring the background noise from the White House.I also suspect that if any of them get fired by POTUS for speaking up (a very real possibility), Biden will scoop them up and put them on his task force.
I'm hoping Biden will put whoever he feels can best perform the job, and not just take someone to spite Donald Trump.
We? Sounds like Pfizer is planning on doing it themselves:https://www.fiercepharma.com/pharma/pfizer-sidelines-us-government-covid-19-vaccine-distribution-plan-favor-its-own-reportshttps://www.fiercepharma.com/manufacturing/pfizer-designed-new-container-and-plans-to-tap-shipping-companies-for-covid-19
Pfizer has been really overt about pointing out that they are doing their own thing separate from OWS today. I wonder why.
A question for the experts here. Obviously there is promising news from Pfizer. The bad news is that their vaccine requires cold storage - up to 100 degrees below zero. My question is - do we have the capability to do this on a large scale? It would seem to preclude giving the vaccine at a doctor’s office. I don’t know that Walgreens or CVS have the capability for storage on the scale that is needed.
They did not take money from the US government if I remember correctly. They were not a part of Warp Speed despite what Pence claimed today. Correct me if I am wrong.
They have not taken money from Warp Speed to help develop the vaccine.However, they are part of Warp Speed's purchase program. The US will buy 100 million doses of an effective vaccine for nearly $2 billion.https://www.nytimes.com/2020/11/09/health/pfizer-covid-19-vaccine.htmlSo Pence isn't 100% wrong when he says they are part of OWS, but federal money had no bearing on the development of the vaccine.
Pence said this was the result of their unprecedented public-private partnership. That is false. It was done without government funds or direction.If someone wants to give a president credit. First credit goes to George Bush, who created the initiative to greatly expand vaccine technology that directly led to the methodologies used here. Second credit goes to Obama, who expanded that initiative. Without them, the decades+ of research that allowed this to be done at all, and also as quickly as it was, would be non-existent.
Although non-trivial, there are ways to get this to work. My lab alone, probably has enough storage for 10k-20k doses or more (depending on size). In other areas, there are alternatives that can be designed. For instance, a storage container surrounded by dry-ice and isopropanol (isopropyl-alcohol), will maintain a temperature cold enough, and can be resupplied with more dry-ice.And Pfizer has a lot of really bright people working on this exact issue for awhile. Off the top of my head, I can come up with about a dozen possible strategies, that given an engineering team and a modest budget and I'm pretty confident I could come up with something that would work. That's just me, who doesn't do logistics for a living. Pfizer has teams of people that have done this a lifetime.
I read this decision was an attempt to distance itself from the potential politics and maximize the number of people willing to take the vaccine, if successful. Not pointed out to say they didn’t benefit from the govt infrastructure that has been helping to speed trials and pre buying doses.
Had two people tell me yesterday they won’t take it