Scholarship table
UK bullish. https://thehill.com/policy/international/europe/492372-top-uk-scientist-80-percent-confident-a-covid-19-vaccine-could-be
St. Luke's in Milwaukee on the forefront of this:https://www.jsonline.com/story/news/2020/04/11/milwaukee-man-stable-after-experimental-coronavirus-plasma-transfusion/2977352001/
Heard a story today that a study of SARS patients showed that in that case, anti-bodies stay in the body and are effective for up to 2 years before starting to drop off by the 3rd year. So if it is similar for COVID and the convalescent plasma treatment is effective, it may not be the same as a vaccine but it could provide similar results until (if) a vaccine is developed.
https://news.yale.edu/2020/04/24/saliva-samples-preferable-deep-nasal-swabs-testing-covid-19Not antibody but another positive toward saliva based which could open up more tests
Dr. Michael Osterholm, the director of the Center for Infectious Disease Research and Policy at the University of Minnesota, told NBC’s Meet The Press “The FDA has all but given up its oversight responsibility for the tests we have on the market,” he added. “Many of them are nothing short of a disaster.”Officials have sounded the alarm about the efficacy of tests currently on the market, criticizing the FDA for greenlighting the products too quickly. The federal government temporarily stripped some of its regulatory barriers after it was scrutinized for its slow rollout of diagnostic tests.On Friday, the House Subcommittee on Economic and Consumer Policy released preliminary findings that showed “wide gaps” in the Trump administration’s handling of antibody testing. “FDA did not review any coronavirus ‘rapid’ antibody test kits before they went on the market, and a lack of enforcement by FDA has allowed manufacturers to make fraudulent claims about their efficacy,” according to the panel’s findings.
I want an antibody test. Anyone know where I could get one in MKE?
Please be aware that depending on which test you get, there may be as high of a 20% false positive rate.So if only 2% of people are infected, for every 1 that tests positive that did have it, 9 will test positive that have never had it.
Some potentially excellent newsIn Race for a Coronavirus Vaccine, an Oxford Group Leaps Ahead"Most other teams have had to start with small clinical trials of a few hundred participants to demonstrate safety. But scientists at the university’s Jenner Institute had a head start on a vaccine, having proved in previous trials that similar inoculations — including one last year against an earlier coronavirus — were harmless to humans."That has enabled them to leap ahead and schedule tests of their new coronavirus vaccine involving more than 6,000 people by the end of next month, hoping to show not only that it is safe, but also that it works."Scientists at the National Institutes of Health’s Rocky Mountain Laboratory in Montana last month inoculated six rhesus macaque monkeys with single doses of the Oxford vaccine. The animals were then exposed to heavy quantities of the virus that is causing the pandemic — exposure that had consistently sickened other monkeys in the lab. But more than 28 days later all six were healthy, said Vincent Munster, the researcher who conducted the test."https://www.nytimes.com/2020/04/27/world/europe/coronavirus-vaccine-update-oxford.html?campaign_id=168&emc=edit_NN_p_20200428&instance_id=17997&nl=morning-briefing®i_id=98421546§ion=topNews&segment_id=26118&te=1&user_id=65badcb7c07b4cd4815fe5e758510381
https://covidtestingproject.org/index.htmlFor those interested in getting antibody tests. You can look here to find which tests are accurate and which are not, and then make sure that your testing company is giving you a good one.
I'm having trouble reading them .. it kinda seems like the tests for antibodies are not very good early, 1-5 "days since onset." 11-15days they are pretty good .. then > 20 days .. maybe they're good, but the dots fade out as if to say they aren't? I would have thought you'd have a ton of antibodies after infection, then fewer as time went on, but maybe my medical degree from Holiday Inn Express is failing me.Then the other chart .. seems to suggest as time goes on, +20 days, the positive tests are way fewer, more negatives. So .. if you were infected 2 months ago, you don't have detectable antibodies anymore? I don't get it.-- Saw this website on the news last night .. $119 and they'll direct you to an office for a blood draw and antibody test .. no idea where the offices are located in the US though: http://getquesttest.com/
It is normal and expected for antibodies to peak late in the infection. In general we have two different immune systems, the innate immune system, and the adaptive immune system. Early in infections the innate immune system tries to clear any foreign infections, it does not have specificity for any specific disease, it is a general response. Later in infection the adaptive immune system kicks in. It is specific to an antigen, and includes the production of antibodies. So we expect that later in the infection there will be more antibodies present and a higher degree of positive antibody tests.